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M94A2967.TXT
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1994-10-25
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Document 2967
DOCN M94A2967
TI Initial report of CD4 counts and oral lesions in a Texas HIV
seropositive cohort.
DT 9412
AU Yeh CK; Puttaiah R; Fabre C; Dove S; Cottone J; UTHSCSA, San Antonio
78284-7919.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):184 (abstract no. PB0164). Unique
Identifier : AIDSLINE ICA10/94369608
AB OBJECTIVE: A prospective surveillance program at an HIV/AIDS dedicated
dental clinic has been developed to monitor HIV associated oral lesions
in relationship to patients' general health. This is a preliminary
report of the baseline data on disease characteristics of dental
patients being treated at this clinic. METHODS: A computerized dental
charting system was used which included information on socioeconomic and
HIV status, dental and medical history, and a comprehensive oral
examination with progress notes. Patients receiving dental service at
the Sansing Dental Clinic, Austin, Texas, were enrolled in this program.
RESULTS: Two hundred forty-eight patient charts were reviewed and
frequency distributions calculated for program variables. Ninety-two
percent were male and 8% female. The mean age was 35 (SD = 7) years, and
majority were non-Hispanic White (61%). Forty-four percent had medical
insurance with only 16% having dental insurance. The mean CD4 count was
262 (SD = 214) and 46.4% having < 200. Approximately 61% took one or
more anti-HIV medications. A total of 171 HIV-related soft tissue oral
lesions (hairy leukoplakia, candidiasis or Kaposi's Sarcoma) and 26
HIV-associated periodontal disease were found. A negative association
between CD4 counts and the number of HIV oral manifestations (R2 =
0.079, p = 0.0001) was noted. In addition, 81 reported xerostomia and 51
reported taste changes. DMFT was 11.2 (SD = 6.2). DISCUSSION AND
CONCLUSIONS: Our data indicates an inverse relationship between the CD4
counts and oral lesions. The computerized surveillance program could be
applied to multiple dental clinic sites to monitor oral health needs,
and to study the impact of oral lesions associated with the progression
of HIV infection.
DE Adult AIDS-Related Opportunistic Infections/*IMMUNOLOGY Candidiasis,
Oral/IMMUNOLOGY Female Human HIV Seropositivity/*IMMUNOLOGY
Leukocyte Count Leukoplakia, Oral/IMMUNOLOGY Male Middle Age Mouth
Diseases/*IMMUNOLOGY Mouth Neoplasms/*IMMUNOLOGY Texas T4
Lymphocytes/*IMMUNOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).